1 2 3 4 Tension - dependent stretching and folding of ZO - 1 controls the localization of its 5 interactors 6 7 8
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Vasoconstrictor mechanisms in the cerebral circulation are unaffected by insulin resistance.
Insulin-resistance (IR) impairs agonist-induced relaxation in cerebral arteries, but little is known about its effect on constrictor mechanisms. We examined the vascular responses of the basilar artery (BA) and its side branches in anesthetized Zucker lean (ZL) and IR Zucker obese (ZO) rats using a cranial window technique. Endothelin-1 (ET-1) constricted the BAs in both the ZL and ZO rats, but...
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تاریخ انتشار 2017