1 2 3 4 Tension - dependent stretching and folding of ZO - 1 controls the localization of its 5 interactors 6 7 8

نویسندگان

  • Domenica Spadaro
  • Shimin Le
  • Thierry Laroche
  • Isabelle Mean
  • Lionel Jond
  • Jie Yan
  • Sandra Citi
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Vasoconstrictor mechanisms in the cerebral circulation are unaffected by insulin resistance.

Insulin-resistance (IR) impairs agonist-induced relaxation in cerebral arteries, but little is known about its effect on constrictor mechanisms. We examined the vascular responses of the basilar artery (BA) and its side branches in anesthetized Zucker lean (ZL) and IR Zucker obese (ZO) rats using a cranial window technique. Endothelin-1 (ET-1) constricted the BAs in both the ZL and ZO rats, but...

متن کامل

ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

Intercellular junctions are crucial for mechanotransduction, but whether tight junctions contribute to the regulation of cell-cell tension and adherens junctions is unknown. Here, we demonstrate that the tight junction protein ZO-1 regulates tension acting on VE-cadherin-based adherens junctions, cell migration, and barrier formation of primary endothelial cells, as well as angiogenesis in vitr...

متن کامل

Heteropolymer Freezing and Design: Towards Physical Models of Protein Folding

Due to its biological signiicance and physical complexity, understanding protein folding has become one of the greatest problems in modern molecular biophysics, bridging ideas from the physics of disordered systems, polymer physics, and molecular biology. We review the statistical mechanics of heteropolymers (chain molecules with quenched disordered sequence of links) as well as the resulting i...

متن کامل

Supplement to Internally 4-connected projective-planar graphs

A5 = {{1, 2}, {1, 3}, {1, 4}, {1, 5}, {2, 3}, {2, 4}, {2, 5}, {3, 4}, {3, 5}, {4, 5}, {6, 7}, {6, 8}, {6, 9}, {6, 10}, {7, 8}, {7, 9}, {7, 10}, {8, 9}, {8, 10}, {9, 10}} C11 = {{1, 2}, {1, 3}, {1, 4}, {1, 5}, {2, 3}, {2, 4}, {2, 5}, {3, 4}, {3, 5}, {4, 5}, {6, 9}, {6, 10}, {6, 11}, {7, 9}, {7, 10}, {7, 11}, {8, 9}, {8, 10}, {8, 11}} E42 = {{1, 4}, {1, 5}, {1, 6}, {2, 4}, {2, 5}, {2, 6}, {3, 4},...

متن کامل

Summer 2016 Homotopy Theory Seminar

1. Simplicial Localizations and Homotopy Theory: 5/24/16 1 2. Simplicial Sets: 5/31/16 3 3. Model Categories: 6/7/16 8 4. Localization: Classical and Bous eld: 6/17/16 12 5. Simplicial Localizations of Categories: 6/21/16 16 6. The Hammock Localization: 6/28/16 20 7. The Indexing Category II: 7/8/16 21 8. Homotopy Calculi of Fractions and You!: 7/19/16 24 9. The Grothendieck Construction: 7/26/...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017